ALS trials

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Info experimental studies

Clinical trials in Belgium...

Transposon studie met TPN-101 in C9orf72 ALS en/of FTD Active but not recruiting 

Wave FOCUS-C9 studie met C9orf72 ASO in ALS en FTD Active and recruiting

HIMALAYA-studie Active and recruiting

MAGNET-studie Active and recruiting

Cytokinetics COURAGE studie met Reldesemtiv Active and recruiting

Ferrer ADORE studie met FAB122 (orale vorm edaravone) Active and recruiting

Biogen ATLAS studie met ASO met presymptomatische SOD1 dragers Active and recruiting

Ionis FUSION studie met FUS ASO Active and recruiting

Apellis MERIDIAN studie met pegcetacoplan in ALS Active and recruiting

Alexion CHAMPION-ALS study Discontinued

Orphazyme Arimoclomol (ORARIALS-01) study Completed

Biogen SOD1 ASO study Active

Biogen Methodology study Completed

PESA study Active and recruiting

PYRAMID study Active and recruiting

REFALS - Levosimendan (ODM-109) Completed

TUDCA study Recruiting

 

Clinical trials abroad in collaboration with the league

TRICALS

 

PRODUCT STUDIE STATUS END DATE RESPONSIBLE FIRM, UNIV, CLINIC OR COUNTRY
AMX-0035 PHOENIX Active Not Recruiting 03/2024 Amylyx

Antiretroviral

X Recruiting 02/2023 NINDS, Australia

Autologe Stamcellen

X     Czech, Mayo, Poland, Korea
Allogene Stamcellen X     Caribbean, universities
BIIB105 ALSpire Recruiting 07/2026 Biogen/Ionis
Cannabinoids EMERALD Recruiting 01/2023 Australia
CU(II)ATSM   Completed 12/2022 Coll Med Dev Australia
Dazucorilant DAZALS Recruiting 06/2024 Corcept Therapeutics
Deferiprone FAIR-ALS II Recruiting 04/2022 France 
DNL3443   Active Not Recruiting 12/2023 Denali
Edaravone oral, FAB122 ADORE Active Not Recruiting 06/2024 Mitsubishi, Ferrer
Fasudil ROCK REAL Active Not Recruiting 07/2023 Germany, France, US
GDNF   Recruiting 09/2023 Cedars Sinai
Healey Platform Trial HEALEY Recruiting   NEALS
Ibudilast (MN-166) COMBAT-ALS Recruiting 12/2024 MediciNova
ION363 fus FUSION Recruiting 03/2024 Ionis
Lithium Magnet MAGNET Recruiting   Tricals
Masinitib   Recruiting 12/2023 AB Science
Memantine and Trazodone SMART Recruiting 12/2026 UK
Pegcetacoplan MERIDIAN Active Not Recruiting 03/2024 Apellis
Presymptomatic sod1 ATLAS Recruiting 08/2027 ...

Biogen

Q-cells

ALTA BOLT Not Yet Recruiting 12/2024 Q Therapeutics
Rapamycin RAPALS Completed 02/2022 Univ Modena
Reldesemtiv COURAGE Recruiting 03/2024 Cytokinetics
RNS60   Not Yet Recruiting 06/2024 Italy and US
SAR443820 HIMALAYA Recruiting 04/2024 Sanofi
BIIB067 Long Term sod1   Active Not Recruiting 06/2024 Biogen/Ionis
TPN-101 C9 Transposon Recruiting 09/2023 Transposon
TUDCA   Active Not Recruiting 12/2022 horizon 2020
WVE-004 Focus C9 Active Not Recruiting 02/2023 wave
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