ALS trials

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Info experimental studies

Clinical trials in Belgium...

PRECISION-ALS  Active and recruiting

QRL-201Active and recruiting

CARDINALS Active nut not recruiting

ActiSLA-studie-CHR-Citadelle-Luik Active and recruiting

AP101-studie  Active and recruiting

Corcept Therapeutics DAZALS studie met CORT113176 (dazucorilant) Active nut not recruiting

Amylyx - Phoenix Active nut not recruiting

Ferrer ADORE study infographic  

Studie met TPN-101 in C9orf72 ALS en/of FTD Active nut not recruiting

Wave FOCUS-C9 studie met C9orf72 ASO in ALS en FTD discontinued

HIMALAYA-studie Active and recruiting

MAGNET-studie Active and recruiting

Cytokinetics COURAGE studie met Reldesemtiv discontinued

Ferrer ADORE studie met FAB122 (orale vorm edaravone) Active nut not recruiting

Biogen ATLAS studie met ASO met presymptomatische SOD1 dragers Completed

Ionis FUSION studie met FUS ASO Active and recruiting

Apellis MERIDIAN studie met pegcetacoplan in ALS discontinued

Alexion CHAMPION-ALS studie discontinued

Orphazyme Arimoclomol (ORARIALS-01) fase III studie Completed

Biogen SOD1 ASO Afgerond Compassionate Use programma

Biogen Methodologie studie Completed

PESA studie Active and recruiting

PYRAMID (Phenotype Research for ALS Modifyer Discovery) studie Active and recruiting

TUDCA studie Completed


Clinical trials abroad in collaboration with the league



AMX-0035 PHOENIX Active Not Recruiting 03/2024 Amylyx


X Recruiting 02/2023 NINDS, Australia

Autologe Stamcellen

X Recruiting   US, Korea

Allogene Stamcellen

X     Caribbean, universities
AP101-02   Recruiting 01/2025 AL-S Pharma
BIIB105 ALSpire Active Not Recruiting 07/2026 Biogen/Ionis
Cannabinoids EMERALD Active Not Recruiting 01/2024 Australia
CU(II)ATSM   Active Not Recruiting 12/2022 Coll Med Dev Australia
Dazucorilant DAZALS Recruiting STOP 18/11/2023 Corcept Therapeutics
Deferiprone FAIR-ALS II Recruiting 04/2022 France 
Fasudil ROCK REAL Active Not Recruiting 1/2023 Germany, France, US
GDNF   Recruiting 09/2025 Cedars Sinai
Healey Platform Trial HEALEY Recruiting 07/2024 NEALS
Ibudilast (MN-166) COMBAT-ALS Recruiting 12/2024 MediciNova
ION363 fus FUSION Recruiting 03/2028 Ionis
Lithium Magnet MAGNET Recruiting 06/2024 Tricals
Masinitib   Recruiting 12/2023 AB Science
Memantine and Trazodone SMART Recruiting 12/2026 UK
Presymptomatic sod1 ATLAS Recruiting 08/2027 ...



ALTA BOLT Not Yet Recruiting 12/2025 Q Therapeutics
QRL-201   On-Hold 05/2025 QurAlis
Rapamycin MONEPANTEL Completed 05/2023 Univ Modena
RNS60   Not Yet Recruiting 06/2026 Italy and US
SAR443820 HIMALAYA Active Not Recruiting 01/2027 Sanofi
BIIB067 Long Term sod1   Active Not Recruiting 06/2024 Biogen/Ionis
TPN-101 C9 Transposon Completed 09/2023 Transposon
TUDCA TUDCA-ALS OLE Active Not Recruiting 03/2025 horizon 2020