ALS trials
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Info experimental studies
Clinical trials in Belgium...
Transposon studie met TPN-101 in C9orf72 ALS en/of FTD Active but not recruiting
Wave FOCUS-C9 studie met C9orf72 ASO in ALS en FTD Active and recruiting
HIMALAYA-studie Active and recruiting
MAGNET-studie Active and recruiting
Cytokinetics COURAGE studie met Reldesemtiv Active and recruiting
Ferrer ADORE studie met FAB122 (orale vorm edaravone) Active and recruiting
Biogen ATLAS studie met ASO met presymptomatische SOD1 dragers Active and recruiting
Ionis FUSION studie met FUS ASO Active and recruiting
Apellis MERIDIAN studie met pegcetacoplan in ALS Active and recruiting
Alexion CHAMPION-ALS study Discontinued
Orphazyme Arimoclomol (ORARIALS-01) study Completed
Biogen SOD1 ASO study Active
Biogen Methodology study Completed
PESA study Active and recruiting
PYRAMID study Active and recruiting
REFALS - Levosimendan (ODM-109) Completed
TUDCA study Recruiting
Clinical trials abroad in collaboration with the league
| PRODUCT | STUDIE | STATUS | END DATE | RESPONSIBLE FIRM, UNIV, CLINIC OR COUNTRY |
| AMX-0035 | PHOENIX | Active Not Recruiting | 03/2024 | Amylyx |
|
Antiretroviral |
X | Recruiting | 02/2023 | NINDS, Australia |
|
Autologe Stamcellen |
X | Recruiting | US, Korea | |
|
Allogene Stamcellen |
X | Caribbean, universities | ||
| AP101-02 | Recruiting | 01/2025 | AL-S Pharma | |
| BIIB105 | ALSpire | Recruiting | 07/2026 | Biogen/Ionis |
| Cannabinoids | EMERALD | Active Not Recruiting | 01/2024 | Australia |
| CU(II)ATSM | Active Not Recruiting | 12/2022 | Coll Med Dev Australia | |
| Dazucorilant | DAZALS | Recruiting | 06/2024 | Corcept Therapeutics |
| Deferiprone | FAIR-ALS II | Recruiting | 04/2022 | France |
| Edaravone oral, FAB122 | ADORE | Active Not Recruiting | 06/2024 | Mitsubishi, Ferrer |
| Fasudil | ROCK REAL | Active Not Recruiting | 11/2023 | Germany, France, US |
| GDNF | Recruiting | 09/2023 | Cedars Sinai | |
| Healey Platform Trial | HEALEY | Recruiting | NEALS | |
| Ibudilast (MN-166) | COMBAT-ALS | Recruiting | 12/2024 | MediciNova |
| ION363 fus | FUSION | Recruiting | 03/2024 | Ionis |
| Lithium Magnet | MAGNET | Recruiting | Tricals | |
| Masinitib | Recruiting | 12/2023 | AB Science | |
| Memantine and Trazodone | SMART | Recruiting | 12/2026 | UK |
| Presymptomatic sod1 | ATLAS | Recruiting | 08/2027 ... |
Biogen |
|
Q-cells |
ALTA BOLT | Not Yet Recruiting | 12/2024 | Q Therapeutics |
| Rapamycin | MONEPANTEL | Active Not Recruiting | 05/2023 | Univ Modena |
| RNS60 | Not Yet Recruiting | 06/2024 | Italy and US | |
| SAR443820 | HIMALAYA | Active Not Recruiting | 04/2024 | Sanofi |
| BIIB067 Long Term sod1 | Active Not Recruiting | 06/2024 | Biogen/Ionis | |
| TPN-101 C9 | Transposon | Recruiting | 03/2025 | Transposon |
| TUDCA | TUDCA-ALS OLE | Active Not Recruiting | 12/2022 | horizon 2020 |
